Dr. Weihong Ge

Research Interests: Brain Tumor Modeling and Mechanisms

Weihong Ge graduated from the Medical School of Fudan University in China and received further training as a developmental neuroscientist at UCLA. Her long-term research focuses on the molecular mechanisms underlying neural stem cell (NSC) differentiation and the potential of stem cell approaches to treat neurological diseases. Her current project centers on studying brain tumors, which reactivate developmental trajectories and cell types similar to neural development—making her previous research highly relevant.

Weihong is currently leveraging the human organoid tumor transplantation (HOTT) system to optimize in vitro brain tumor models. This allows her to investigate the molecular mechanisms underlying the progression of brain tumor progenitors and their interaction with the tumor microenvironment. The HOTT system features time scales suitable for clinical practice, paving the way for personalized medicine to treat brain tumors, including individual drug screening and drug resistance assessment.

Outside the lab, Weihong enjoys outdoor activities such as hiking with friends and traveling with her family.